加入我們創(chuàng)新的裂解酶研發(fā)團隊 我們正在尋找一位積極進取、技術精湛的博士級科學家加入我們充滿活力的團隊。我們是一家在裂解酶領域擁有廣泛國際影響力的領先公司,擁有多款一流的產(chǎn)品。 工作內容: 您將在研發(fā)新型裂解酶的過程中發(fā)揮關鍵作用,并將其用于治療耐藥細菌。您將加入我們世界領先的溶菌素研發(fā)平臺,并在兩位來自美國頂尖大學的博士科學家的指導下開展工作。 工作職責包括領導一個研發(fā)項目,以識別和驗證針對特定目標生物體的靶分子。以下技能對于成功的候選人至關重要: ? 分子生物學:設計和執(zhí)行涉及分子克隆的實驗,包括質粒構建、PCR引物設計和測序結果分析。 ? 微生物學:分離和操作菌株,尤其是苛性厭氧菌,嚴格遵守無菌操作規(guī)程,并進行MIC測試、生物膜研究以及厭氧操作臺的使用等實驗。 ? 實驗開發(fā):具備高通量篩選和96/384孔板實驗經(jīng)驗。具備機器人系統(tǒng)使用經(jīng)驗者優(yōu)先! ? 蛋白質科學:運用多種生化技術純化和表征重組蛋白。 ? 數(shù)據(jù)管理:維護詳細準確的實驗數(shù)據(jù)記錄,并及時向團隊負責人提交報告。 我們尋求的人才: ? 獨立且清晰的科學思維:能夠開發(fā)、設計和開展創(chuàng)新研究。能夠理解科學論文和專利。 ? 團隊合作:我們的研發(fā)團隊是一個團結協(xié)作、廣泛合作的團隊。您必須能夠有效地協(xié)作以實現(xiàn)您的目標。 ? 教育背景:該職位要求博士學位。學科方向可為微生物學、生物技術或相關領域。 ? 經(jīng)驗:雖然擁有行業(yè)經(jīng)驗者優(yōu)先,但我們更看重擁有扎實基礎知識和科研熱情的候選人。我們非常重視之前與致病菌相關的工作經(jīng)驗。 ? 技能:具備強大的分析和解決問題能力。能夠設計和執(zhí)行邏輯清晰、定義明確的實驗。優(yōu)秀的書面和口頭溝通能力(大學英語六級或同等水平)。您需要能夠用英語撰寫報告。 ? 加分項:具備在良好實驗室規(guī)范 (GLP) 環(huán)境下工作的經(jīng)驗;動物模型(小鼠/大鼠)使用經(jīng)驗;熟悉不同的蛋白表達系統(tǒng)(例如,無細胞表達系統(tǒng)、酵母表達系統(tǒng)等);能夠使用 Python 編程。 Join Our Innovative Endolysin Discovery Team We’re seeking a highly motivated and skilled PhD-level Scientist to join our dynamic team. We are a leading company with large international footprint in the endolysin field with several best-in-class products. What You’ll Do: You’llplay a crucial role in the discovery of novel endolysins for use as therapeutics to solve the problem of drug-resistant bacteria. You will join our world-leading endolysin discovery platform and work under the supervision of two PhD scientists from a top-tier US university. Responsibilities will include leading a discovery project to identify and validate target molecules for defined target organisms. The following techniques are important for a successful candidate: · Molecular Biology: Designing and executing experiments involving molecular cloning – including plasmid construction, PCR primer design, and analysis of sequencing results. · Microbiology: Isolating and working with bacterial strains, especially fastidious anaerobic bacteria, maintaining strict sterile techniques, and performing assays such as MIC testing, biofilm studies, and utilizing an anaerobic hood. · Assay Development: Experience with high throughput screening and 96/384-well plate assays. Experience with robotic systems is a plus! · Protein Science: Purifying and characterizing recombinant proteins, utilizing a range of biochemical techniques. · Data Management: Maintaining detailed and accurate records of experimental data and preparing timely reports for the team lead. What We’re Looking For: · Independence and clear scientific thinking: Ability to develop, design, and perform innovative research. Ability to understand scientific articles and patents. · Team work: Our discovery team is a cohesive team that collaborates extensively. You must be able to collaborate effectively to achieve your goals. · Education: PhD degree is an absolute requirement for this position. Subject could be in Microbiology, Biotechnology, or a related field. · Experience: While prior industry experience is an advantage, we value candidates with strong foundational knowledge and a passion for research. We greatly value prior experience working with pathogenic bacteria. · Skills: Strong analytical and problem-solving skills. Ability to design and execute logical and well-defined experiments. Excellent written and verbal communication skills (CET-6 or equivalent proficiency in English).You will be expected to be able to write reports in English. · Bonus Points: Experience working in a GLP environment; experience with animal models (mouse/rat);experience with different protein expression systems (for example, cell-free expression system, yeast expression system, etc.); ability to program in python.